Adverse childhood environment and late-life cognitive functioning
نویسندگان
چکیده
منابع مشابه
Association of adverse childhood environment and 5-HTTLPR Genotype with late-life depression.
OBJECTIVE Neurobiological and clinical studies suggest that childhood maltreatment may result in functional and structural nervous system changes that predispose the individual to depression. This vulnerability appears to be modulated by a polymorphism in the serotonin gene-linked promoter region (5-HTTLPR). Little is known, however, about the persistence of this vulnerability across the life s...
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BACKGROUND Late-life depression is a heterogeneous disorder, whereby cognitive impairments are often observed. This study examines which clinical characteristics and symptom dimensions of late-life depression are especially impacting on specific cognitive domains. METHODS Cross-sectional data of 378 depressed and 132 non-depressed older adults between 60-93 years, from the Netherlands Study o...
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BACKGROUND The literature describing neurocognitive function in patients with late-life depression (LLD) show inconsistent findings in regard to incidence and main deficits. Reduced information processing speed is in some studies found to explain deficits in higher order cognitive function, while other studies report specific deficits in memory and executive function. Our aim was to determine t...
متن کاملCognitive functioning and the natural course of depressive symptoms in late life.
OBJECTIVES To investigate whether specific domains of cognitive functioning predict the natural course of depressive symptoms in older people. DESIGN AND PARTICIPANTS Using the nationally representative, population-based cohort of the Longitudinal Aging Study Amsterdam, 281 participants with clinically relevant depressive symptoms (Center for Epidemiological Studies Depression Scale ≥16) aged...
متن کاملPrenatal drug exposure: behavioral functioning in late childhood and adolescence.
The knowledge base on the long-term implications of prenatal drug exposure in human development is extremely limited, but suggests that children with drug-using parents are at high risk for nonoptimal development. The literature, however, provides some evidence that this risk is related to environmental factors. To date, there is no compelling evidence that history of prenatal drug exposure aff...
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ژورنال
عنوان ژورنال: International Journal of Geriatric Psychiatry
سال: 2010
ISSN: 0885-6230
DOI: 10.1002/gps.2553